An indicator that the symptomatic individuals might have lung and/or gut tissue damage related to COVID-19 is the high levels of TNFSF14 detected by PEA, and as reported before this protein is implicated in lung fibrosis when produced by local fibroblasts acting in tissue remodeling (91) but also play a role in limiting inflammation in an animal model of chronic colitis (92). This evidence concerns the gene TNFSF14 and Chronic colitis.