In a mite allergen model of allergic asthma, in vitro exposure of Dermatophagoides farinae (Derf)-sensitized CD4+ T cells to the antigen increased desialylation of cell surface glycoconjugates, augmented binding of hyaluronic acid (HA) to its cognate receptor, CD44, and heightened NEU1, but not NEU2 or NEU3, transcript levels (30). This evidence concerns the gene NEU1 and allergic asthma.