This subpopulation expresses chemokine receptor type 5 (CCR5) as the primary HIV-1 acceptor, as well as lower levels of CCR2 in contrast to classical monocytes, which induces this type of monocytes to move to the site of infection and invade tissues through CCR2/chemokine ligand 2 (CCL2) (24). Here, CCR2 is linked to infection.