In EBV+ Hodgkin lymphoma (HL) and EBV+ nodal diffuse large B cell lymphoma (DLBCL) young patients, immune escape plays an important part in pathogenesis, as evidenced by recurrent alterations in PD-L1 and PD-L2 (4, 5). The gene discussed is PDCD1LG2; the disease is Hodgkins lymphoma.