For instance, the LUCAT1/miR-5582-3p/TCF7L2 axis adjusts breast cancer stemness via the Wnt/β-catenin pathway (64), and LUCAT1 promotes the occurrence and development of esophageal squamous cell carcinoma, colorectal cancer, and gastric cancer by controlling the ubiquitination and stability of DNA methyltransferase 1 (65). Here, TCF7L2 is linked to esophageal squamous cell carcinoma.