In addition, mutation or de-regularization of kinase activity has been proven to be oncogenic and has potential to inhibit the spread of cancer cells.17 Considering that kinases play an important role in cell biology, many attempts have been made to develop novel kinase inhibitors such as tyrosine kinase,18 cyclin-dependent kinase,19–21 aurora kinase,22,23 EGFR24 and VEGFR,25 which can serve as potential drugs candidates. Here, KDR is linked to cancer.