As for mutation in the non-coding area, patients with SCA8, SCA10, and SCA12 present cognitive dysfunction or dementia (Gatchel and Zoghbi, 2005; Lindsay and Storey, 2017; Giocondo and Curcio, 2018), (CTG)n repeats in Ataxin8 3'UTR causes SCA8 (Koob et al., 1999), (ATTCT)n in Ataxin10 intron results in SCA10 (Matsuura et al., 2000), and (CAG)n in PPP2R2B 5'UTR leads to SCA12 (Holmes et al., 1999). Here, ATXN10 is linked to dementia.