Data from clinical studies found that prior to Atezolizumab, the percentage of tumours with PD-L1 expression of >5% IC varied from 27% (previously untreated tumours in Cisplatin ineligible patients) to either 28% or 33% in those who had prior chemotherapy treatment (28% in metastatic tumour samples, 33% in primary tumour samples) [11,12]. The gene discussed is CD274; the disease is neoplasm.