Moreover, in HCC patient tissue, CD66b+ neutrophils and CXCR2+ cells predominantly localised to NASH-HCC tumours with expression of the two markers correlating, and furthermore being demonstrated to be colocalised at the cellular level (figure 2G, H and online supplemental figure 2J, K). The gene discussed is CXCR2; the disease is metabolic dysfunction-associated steatohepatitis.