IMC neighbourhood analysis revealed intimate associations of MPO+Ki67+ neutrophils with CD8+ T cells and MHC Class II+ (MHCII+) antigen presenting cells (APCs) that were found in the regions of interest with six out of seven AZD5069/anti-PD1 treated tumours that were examined by IMC (figure 5G–I). Here, CD8A is linked to neoplasm.