Next, in order to further verify the specificity of relationship between ALDH2 and PTX resistance, we transiently silenced ALDH2 and other CSCs-related ALDH subtypes (ALDH1A1 and ALDH3A1) and determined the sensitivity of NSCLC/PTX cells to PTX. Here, ALDH1A1 is linked to non-small cell lung carcinoma.