To confirm the function of TLNC1 in tumor progression and metastasis of liver cancer, we silenced TLNC1 using 3 independent short hairpin RNAs (shRNAs) in SNU449 and HCCLM3 cells (Fig. 3a and Fig. S4a) and chose 2 shRNAs with better knockdown efficacy for subsequent experiments. Here, LINC01134 is linked to liver cancer.