KHDRBS1 and renal cell carcinoma: To further confirm the impact of Sam68 in the sunitinib treatment of RCC, HK2, 769P and SKRC39 cells were used to constructed exogenous Sam68‐overexpression cell line while Caki‐1 and NC‐65 cells were selected to established Sam68‐knockdown cell lines (Figure 3A,B; Figure S1B).