INS and Hypoglycemia: However, to fully exploit SMBG and achieve glucose targets, SMBG should be performed in a structured manner (e.g., before meals and snacks, at bedtime, occasionally postprandially, before exercise, when hypoglycemia is suspected, before driving, etc.), and the results need to be accurately interpreted and used to guide adjustments in medications, especially insulin, and to modify food intake and/or physical activity [7, 8].