FKBP5 and obesity due to melanocortin 4 receptor deficiency: Tarryn Willmer et al. [34] obtained abdominal SAT and gluteal SAT from 27 obese and 27 normal weight urban-dwelling South African women and found that the methylation level of FK506-binding protein 51 kDa (FKBP5) gene was associated with obesity and insulin resistance.