TNF and myeloproliferative disorder: Using Spearman correlations as an alternative way to investigate TNF-α and the microbiome, we found that the genus Parabacteroides may also be associated with TNF-α production in MPN; however, this trend was not significant after correcting for multiple comparisons (r = 0.65, P = 0.016, q = 0.77) (Fig. S2).