CD40LG and infection: In contrast, IgD+IgMlow classical MBCs and two populations of atypical MBCs (IgM+IgD+ and class‐switched T‐bet+ cells) expressing low or no CXCR5 and CCR6, along with CD127+CD25low TH2‐like memory CD4+ T cells, were associated with reduced odds of symptomatic infection (Fig 3F).