FGD5 and osteosarcoma: Li et al. [70] also reported that FGD5-AS1 contains the binding site of the miR-506-3p seed sequence, which can negatively regulate the expression of miR-506-3p and weaken the inhibitory effect of miR-506-3p on the mRNA and protein expression of RAB3D, thereby promoting its high expression and the progression of osteosarcoma.