Not only did RNA-seq detect common fusions such as BRAF-KIAA1549 in 4 pilocytic astrocytomas, but it also detected rarer fusions including 2 cases with NTRK fusions, and one with a clear MYBL1 driver in an infiltrating astrocytoma. The gene discussed is KIAA1549; the disease is astrocytoma (excluding glioblastoma).