have reported that enhanced PD‐1 expression on eTregs (Figure 1) was observed in low‐glucose TME of HCC on account of eTregs actively absorbed LA through monocarboxylate transporter 1 (MCT1) and promoted nuclear factor of activated T cells‐1 (NFAT1) translocation into the nucleus.165. This evidence concerns the gene PDCD1 and hepatocellular carcinoma.