After METTL3 pcDNA 3.1 (pc-METTL3) was transfected into glioma cells (p < 0.05, Fig. 3J–K), the m6A level in cells, circDLC1 expression, and m6A level of circDLC1 were also increased (p < 0.01, Fig. 3L–N). This evidence concerns the gene METTL3 and central nervous system cancer.