In leukemia, although promyelocytic leukemia is well known for its relatively good prognosis, Jann et al. analyzed whole transcriptomes of different acute myeloid leukemia cases and found that fibulin-3 was one of the most expressed factors in cases of early promyelocytic leukemia deaths in comparison with the cases with prolonged remission. This evidence concerns the gene EFEMP1 and acute promyelocytic leukemia.