In addition, the expression of RIPK2 is positively correlated with IL-6, IL-8 and VEGF, which play a role in colorectal cancer, indicating that RIPK2 may be involved in the occurrence of colorectal cancer and that the expression level of RIPK2 is correlated with the prognosis of colorectal cancer [24]. Here, CXCL8 is linked to colorectal cancer.