Several clinical parameters, including disease activity score 28 (DAS28), C-reactive protein (CRP), and age, were negatively correlated with UHRF1 mRNA expression levels in RA synovium, whereas there was no correlation with levels of DNMT1, DNMT3A, and DNMT3B (Figure 6B and Supplemental Figure 5, B–E). The gene discussed is CRP; the disease is rheumatoid arthritis.