PLAC8 and rheumatoid arthritis: We used RT-qPCR to validate that Uhrf1 deficiency altered expression of cytokine- and RA-related genes, including Ccl20, Tnfsf11, Ccl5, and Csf3 (Figure 5G), and antiapoptosis-related genes, including Wnt5a and Plac8 (Figure 5H).