Two defensins (DEFA and DEFD) were enriched, as well as two peptidoglycan-degrading amidases (PGRP-SC1, and PGRPS4), orthologs of which, in Drosophila, modulate the activation of the immune deficiency (IMD) pathway (Buchon et al., 2009). The gene discussed is PGLYRP1; the disease is Immunodeficiency.