From bioinformatics analysis, positive correlations were discovered between the expressions of LINC01315 with those of DPEP1, KRT22, ASCL2, and AXIN2, while a negative correlation was found between the expressions of LINC01315 and DUSP4, indicating the effects of LINC01315 in colorectal cancer might be realized by interacting with these genes. This evidence concerns the gene AXIN2 and colorectal cancer.