BCL2 and colorectal cancer: As shown in Figure 6(f–j), exosomes derived from CD133+/CD44+ colorectal cancer cells after being transfected with LINC01315 up-regulated BCL-2, MMP-9, and Vimentin, whereas down-regulated Bax, cleaved caspase-3, and E-cadherin in colorectal cancer cells (P < 0.05).