NFKB1 and rheumatoid arthritis: TRMs from C15 and C29 were highly expressed the pro‐inflammatory cytokine, TNF‐α, that mediate tissue pathology in rheumatoid arthritis[21] and IBD.[10b] We indeed observed significant enrichment of the TNF‐alpha signaling via nuclear factor‐κB (NF‐κB) pathway in these two groups.