TNF and rheumatoid arthritis: It was launched whenanti-tumor necrosis factor (TNF) therapies became available.21 Similarly, SCQM is a Swiss registry established in 1997 and allowedrheumatologists to follow their RA patients to improve outcomes.22 In addition to baseline DAS28, nine patient-level covariates were availablefrom both RCTs and NRS at baseline: gender, age, disease duration, body mass index,baseline rheumatoid factor, number of previous DMARDs and anti-TNF agents, baselinehealth assessment questionnaire disability index, and baseline erythrocytesedimentation rate (ESR).