The following keywords and Mesh terms were combined to improve the sensitivity and specificity of the search strategy: “systemic lupus erythematosus”, “SLE”, “human lymphocyte antigen”, “HLA”, “HLA-DRB”, “HLA-DRB1”, “polymorphism”, “SNP”, “single nucleotide polymorphism”, “variation”, and “mutation”. Here, HLA-DRB1 is linked to systemic lupus erythematosus.