The real time RT-PCR study showed the statistically significant decrease in Bdnf and Cav1 expression levels in the brain of diabetes mice compared to control group (95% CI [0.8708, 1.133], *p < 0.05, F = 1.484; 95% CI [0.8545, 0.9418], *p < 0.05, F = 1.538; Fig. 8A,B, respectively). This evidence concerns the gene CAV1 and diabetes mellitus.