Viral infection also caused increases of GnRH and LH, which acts upstream to regulate the level of progesterone in vivo.67,68 Analysis of the sex-related hormone-testing reports of SARS-CoV-2-infected patients and healthy individuals indicated that SARS-CoV-2 infection also increased serum progesterone and LH levels. The gene discussed is GNRH1; the disease is viral infectious disease.