Western blot assay results revealed that relative to oe-NC + sh-NC treatment, there was no obvious change in the expression of RAD21 in the tumor tissues after oe-LINC00858 + sh-NC treatment, while the expression of PCNP and phosphorylation levels of STAT3 and STAT5 were increased in the tumor tissues following oe-LINC00858 + sh-NC treatment. The gene discussed is PCNP; the disease is neoplasm.