MDM2 and neoplasm: Relative to the mice inoculated with oe-JMJD2C + sh-NC-treated MUM-2B cells, the mice inoculated with oe-JMJD2C + sh-IL5RA-treated MUM-2B cells showed insignificant change in the expression of JMJD2C, MDM2, and p53 but a reduced IL5RA protein level in the tumor tissues (Figs. 6A and S4K).