In order to assess the translational potential of this novel profibrotic remodelling biomarker in DMD, we immunodetected COMP in muscle sections from DMD patients and controls, confirming the exclusive presence of a high number of COMP-positive cells in the muscle of patients, compared to an almost undetectable level in controls (Fig. 7i–k). This evidence concerns the gene COMP and Duchenne muscular dystrophy.