We used GSCALite to analyse the function of CXC chemokines of PDAC in the famous cancer-related pathways (the TSC/mTOR, RTK, RAS/MAPK, PI3K/AKT, hormone ER, hormone AR, epithelial–mesenchymal transition (EMT), DNA damage response, cell cycle, and apoptosis pathways). Here, AKT1 is linked to cancer.