Ala Litman and coworkers explained the importance of the CXCL8-CXCR2 axis in pancreatic cancer, which indicate that the serum chemokine CXCL8 is a better diagnostic and predictive marker than CXCR2, C-reactive protein, classic CA 19-9, and CEA protein [15]. The gene discussed is CXCL8; the disease is familial pancreatic carcinoma.