KSR2 and hepatocellular carcinoma: KSR2-overexpressing cells treated with sorafenib (20 μg/mL, 48 h, according to Fig. 5B) had a higher survival rate than control cells (20 μg/mL, 48 h), but reducing 14–3-3ζ levels enhanced HCC cell sensitivity to sorafenib (Fig. 7E-H).