in an R26R reporter mouse with GFAP-Cretg/+;Pcdh10allfl/fl;p53fl/fl;Rbfl/fl genotype both the site of pinnal elastic cartilage and the whole pinnal tumor were lacZ-positive (Fig. 7G); two cell lines, which were obtained from such pinnal tumors, expressed lacZ homogeneously in vitro (Fig. 7H), but not Pcdh10; iii. The gene discussed is GFAP; the disease is neoplasm.