FOXF1 and colorectal carcinoma: In addition, the FOXF1 expression level was significantly increased in CRC, and FOXF1 overexpression promoted the epithelial-mesenchymal transition, angiogenesis, and chemoresistance of CRC [35, 36], suggesting that FOXF1 may be an oncogene in CRC and is selected as downstream of miR-375-3p.