Similarly, the mRNA (4.0 fold vs Lv-NC group) and protein expression levels of VEGFA in CRC cells were significantly increased by LINC00022 upregulation, while LINC00022 silencing decreased their levels (mRNA, 0.4–0.6 fold vs Lv-anti-NC group, Fig. 5b and 5c). Here, VEGFA is linked to colorectal carcinoma.