Two MAPKAPK5-AS1 shRNAs (sh-MAPKAPK5-AS1#1 and sh-MAPKAPK5-AS1#2) were utilized to silence MAPKAPK5-AS1 in HCC cell lines to successfully construct the low expression model of MAPKAPK5-AS1 (Fig. 2A). Here, MAPKAPK5 is linked to hepatocellular carcinoma.