In addition, we found that the expressions of MAPKAPK5-AS1 and ZEB1 mRNA in HCC-derived cell lines HepG2 and Huh7 were significantly up-regulated compared to L02, and miR-429 expression was significantly lower in HCC-derived cell lines (Fig. 1M-O). The gene discussed is MAPKAPK5; the disease is hepatocellular carcinoma.