Since this promoting effect is observed in multiple viral strains (NL4-3, CC_CH077 and TF_CH077) and multiple cell lines (Jurkat and SupT11 cells) as well as primary human CD4+ T cells, the promotion of HIV-1 infection by IFN-α is not specific for certain viral strains or CD4+ T cell lines. This evidence concerns the gene IFNA1 and HIV-1 infection.