IFNA1 and infection: On the other hand, we also found that Rcf of CH077_CC is significantly increased by IFN-α treatment (Fig 5D; 50% increase, p<1×10−6) to a value close to 2, which when combined with Rcc being less than 1 implies that cell-free infection in the main route of CH077_CC infection in the presence of IFN-α.