IFNA1 and infection: A simple modification to consider this effect is assuming a virus density-dependent cell-free infection rate as follows:dT(t)dt=gT(t)(1−T(t)+I(t)K)−β(1+kV(t)V50+V(t))T(t)V(t)−ωT(t)I(t),(4)dI(t)dt=β(1+kV(t)V50+V(t))T(t)V(t)+ωT(t)I(t)−δI(t),(5)dV(t)dt=pI(t)−cV(t),(6)where k and V50 describe the effect of IFN-α in promoting cell-free infection by IFN-α, with k being the maximum effect and V50 being the viral load inducing 50% of the maximum promotive effect.