miR-524-5p overexpression reduced the protein expression of METTL3 and SOX2 in A549/DDP and H1299/DDP cells, while miR-524-5p knockdown cased the opposite effects (Figure 4(M,N)), suggesting that miR-524-5p negatively regulated the protein expression of METTL3 and SOX2 in NSCLC cells. The gene discussed is SOX2; the disease is non-small cell lung carcinoma.