Additionally, we reported on widespread deficiency of ASS1 in a majority (74%) of 102 primary choroidal and ciliary body melanomas, despite the known 60–80% loss of BAP1 in uveal melanoma (Harbour et al., 2010; Khadeir et al., 2005; Shah et al., 2013). Here, ASS1 is linked to malignant ciliary body melanoma.