The kinase GCN2 is activated by amino acid shortage, PKR by double‐stranded RNA during viral infections, HRI by heme deficiency and PERK (or PEK) by accumulation of misfolded proteins in the endoplasmic reticulum (Sonenberg & Hinnebusch, 2009; Wek, 2018). Here, EIF2AK3 is linked to viral infectious disease.