CBR3 and neoplasm: Table 1 showed that high CBR3-AS1 expression was closely related to larger tumor size (P = 0.034), distant metastasis (P = 0.037), and advanced TNM stage (P = 0.033) in CRC patients. Moreover, survival analysis showed that CRC patients with high CBR3-AS1 expression had shorter overall survival compared to those with low CBR3-AS1 expression (P = 0.006; Figure 1(c)).