We further analyzed the differential expression of PSMC1, NAGK, AREG, DDOST, ATP6V1E1, KDELR1, PLOD2, TMED10, ALG5, ARF3, and OST4 in HNSCC and normal head and neck tissues and found that compared with normal tissues, there are 11 glycosyl groups in HNSCC tissues. The gene discussed is PLOD2; the disease is head and neck squamous cell carcinoma.