By analyzing the multiple published mRNA expression profiles (GSE 18520, GSE 13525, GSE 73935) obtained from NCBI (https://www.ncbi.nlm.nih.gov/geo/), we found that the level of FAM46A mRNA was not only upregulated in ovarian cancer tissues compared with normal tissues (Figure 1(a)), but also significantly upregulated in ovarian cancer cell lines with platin treatment or CDDP-resistance (Figure 1(b–c)). This evidence concerns the gene TENT5A and ovarian cancer.