We found significant increases in pro-BDNF levels across all regions in stroked mice treated with r-hGH compared with saline (peri-infarct, Stroke + Saline fold change (FC) = 1.24 ± 0.12, Stroke + r − hGH (FC) = 1.56 ± 0.19, p = 0.0011; hippocampus, Stroke + Saline FC = 0.83 ± 0.05, Stroke + r − hGH FC = 1.08 ± 0.19, p = 0.0033; and thalamus, Stroke + Saline FC = 1.13 ± 0.15, Stroke + r − hGH FC = 1.53 ± 0.34, p = 0.0076) (Figure 1(b), Table 2). Here, GH1 is linked to stroke disorder.