Lorente and colleagues analyzed the role of SUMO1 pathway in controlling BC tumorigenesis, cancer survival and invasiveness by either depleting SUMO1 and Ubc9 or by exposing to ginkgolic acid C15:1 or 2-D08 (two SUMOylation inhibitors) (Lorente et al., 2019). This evidence concerns the gene SUMO1 and cancer.