AIF1 and brain edema: We found that a) WBV alleviates TBI-induced brain edema, without effect on animal body weight; b) WBV suppresses expression of GFAP and Iba-1 after TBI; c) WBV differently regulates inflammatory cytokines; d) WBV ameliorates neuronal cell death after TBI; and e) WBV improves motor and cognitive function following TBI.