RXRA and metabolic dysfunction-associated steatotic liver disease: Specifically, bioinformatics analysis demonstrated that RXRα expression is downregulated in the livers of patients with liver cirrhosis caused by hepatitis B virus (HBV), hepatitis C virus, and nonalcoholic fatty liver disease (NAFLD), and is also downregulated in HSCs that are activated in vivo in carbon tetrachloride (CCl4)-induced LF mice (He et al., 2020).