GOLPH3 and cancer: The GOLPH3-dependent oncogenic effect is then exerted by specific GSL species which most likely act on adhesion molecules, and Receptor Tyrosine Kinases (RTKs) promoting cancer growth and metastasis (Kovbasnjuk et al., 2005; Russo et al., 2016; Jacob et al., 2018; Russo et al., 2018; Furukawa et al., 2019; Rizzo et al., 2021).